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Older woman taking antibiotics

Treat UTIs early in older adults 'to minimise sepsis risk'Subscription

Delaying or withholding antibiotics in older adults with urinary tract infections is associated with an increased risk of bloodstream infection and all-cause mortality, research published in The BMJ has shown.

Aspirin tablets close up

Aspirin increases bleeding risk in patients receiving warfarinSubscription

Compared with patients taking warfarin monotherapy, those taking aspirin and warfarin were at a higher risk of a bleeding event but the rate of thrombotic events was similar.

igg monoclonal antibody

Early intensive therapy may delay MS progressionSubscription

Early aggressive therapy for multiple sclerosis is associated with improved long-term outcomes compared with an escalation approach, a study in JAMA Neurology has shown.

Coloured transmission electron micrograph (TEM) of human papillomavirus

High-risk HPV infection linked to increased risk of cardiovascular disease Subscription

Women with high-risk human papillomavirus infection are more likely to develop cardiovascular disease than those without, the results of a study published in Circulation Research suggest.

Older person hands

Exercise interventions reduce falls in older adultsSubscription

The rate of falls in older adults living in the community can be effectively reduced with exercise interventions, the authors of a recent Cochrane review have concluded.

Hydrocodone bottle

Prodrug opioids less effective in patients on SSRIsSubscription

Direct acting, rather than prodrug, opioids should be considered for postoperative pain relief in patients with depression receiving selective serotonin reuptake inhibitors, researchers have found.

Rhinovirus

Enzyme mouth spray could shorten cold durationSubscription

An oral spray containing a proteolytic enzyme reduced the severity and duration of the common cold, a randomised study has found.

Box of needles and syringes

Needle and syringe programmes cost effective in reducing HCV transmissionSubscription

Study shows needle and syringe programmes reduce transmission of hepatitis C while delivering cost savings.

Prostate cancer cells

Long-term follow-up allays fears that finasteride increases mortality Subscription

Initial concerns that finasteride could increase risk of prostate cancer death have been found to be unwarranted in a long-term follow-up study.

Man drinking alcohol

Naltrexone not associated with serious adverse events, review findsSubscription

The opioid antagonist naltrexone does not appear to increase the risk of serious adverse events over placebo, researchers from the University of Manchester have found.

X-ray of hip joint

Study questions link between antidepressants and hip fracturesSubscription

A previously identified link between antidepressant use and hip fractures needs further examination, the authors of a study published in JAMA Psychiatry have concluded.

Vitamin D capsules

Monthly vitamin D dosing has no significant effect on bone mineral densitySubscription

Monthly dosing of vitamin D3 supplements in older adults does not increase bone mineral density, the results of a recent study show.

Patient-centred consultation

Patient-centred clinic improves outcomes after myocardial infarctionSubscription

A post-myocardial infarction medicines optimisation clinic, led primarily by a pharmacist with support from a cardiologist, has resulted in improved medicines adherence and guideline concordance, study results published in Open Heart show.

Osteoarthritis knee X ray

Uncertainty on long-term efficacy of osteoarthritis medicinesSubscription

There is a lack of evidence that medicines for osteoarthritis are effective in the long term, according to a review in the Journal of the American Medical Association.

Woman injecting insulin

Sulfonylureas and basal insulin linked to elevated cardiovascular riskSubscription

Sulfonylureas and basal insulin confer an increased risk of cardiovascular events compared with newer second-line medicines for type 2 diabetes mellitus, research has found.

Hospital corridor

Statins and metformin could be used to treat serious mental illnessSubscription

Existing medicines for physical conditions such as diabetes and hypertension could be used to treat serious mental illness, concluded the authors of a recent study in JAMA Psychiatry.

Physician testing spasticity in motor neurone patient

Cannabinoids could help manage spasticity in motor neurone diseaseSubscription

An oral spray containing cannabinoids is effective at reducing spasticity symptoms in motor neurone disease, study results have shown.

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