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Increased intensity adherence maximises statin benefitsSubscription

High adherence to intensive lipid-lowering therapy provides the greatest risk reduction for cardiovascular events, a study in JAMA Network Open has shown.

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First-line immunotherapy does not improve survival in metastatic lung cancerSubscription

Single or combination first-line immunotherapy does not significantly extend survival compared with chemotherapy in metastatic non small-cell lung carcinoma, trial results have shown.

Woman exercising in park

Exercise may be as effective as medicines in hypertensionSubscription

Exercise interventions are as effective in reducing systolic blood pressure as many antihypertensive medicines in people with hypertension, according to the results of a network meta-analysis published in the British Journal of Sports Medicine.

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Smokers who use e-cigarettes no more likely to quit in the long term, study findsSubscription

People who use e-cigarettes alongside traditional cigarettes are no more likely to quit smoking in the long term than those who only smoke cigarettes, research has shown.

Cardiologist treating AF using cathether ablation

Depression linked to atrial fibrillation diagnosisSubscription

Depression is associated with an increased likelihood of atrial fibrillation diagnosis, according to a study published in the European Journal of Preventive Cardiology.

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Obesity increases risk of childhood asthma by 29%, say researchersSubscription

Obesity is a major preventable cause of childhood asthma, conclude the authors of a study published in Paediatrics.

Secondary lymph node cancer

Pembrolizumab extends survival in recurrent head and neck cancerSubscription

A study of nearly 500 patients with head and neck cancers reveals that pembrolizumab could extend survival compared with methotrexate, docetaxel or cetuximab, which are the standard of care.

Night shift worker

Night shifts and unhealthy lifestyles both increase risk of T2DMSubscription

Researchers have found evidence suggesting that the benefits of adhering to a healthy lifestyle could be even greater in people who work rotating night shifts.

Obese child standing on scales

Early life exposure to antibiotics and acid suppressants increases obesity riskSubscription

Exposure to antibiotics and acid suppressants in the first two years of life is associated with an increased risk of obesity later in childhood, particularly if prescribed in combination, study results show.

Neisseria gonorrhoeae bacteria

Antibiotic with novel mode of action effective against gonorrhoea infectionSubscription

A novel antibiotic, which prevents bacterial cells from replicating DNA, is effective in the treatment of uncomplicated urogenital gonorrhoea, results from a phase II clinical trial have shown.

Prostate cancer cells

Androgen deprivation therapy 'increases heart failure risk'Subscription

Patients with prostate cancer treated with androgen deprivation therapy were 72% more likely to experience heart failure than those unexposed to the therapy, a study has shown.

Pregnant woman taking a tablet

Neurotransmitter-affecting medicines used in pregnancy not linked to autism risk in offspringSubscription

Use of medicines targeting neurotransmitter systems during pregnancy is unlikely to influence estimates of autism spectrum disorder (ASD) in offspring, the authors of a study published in JAMA Psychiatry have concluded.

Statins blister packs

First-year statin discontinuation and non-adherence common in older adultsSubscription

A substantial proportion of older people who begin taking statins do not take them as intended, according to an Australian study published in the British Journal of Clinical Pharmacology.

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ACEIs linked to increased risk of lung cancerSubscription

An observational study of almost one million people suggests a link between angiotensin converting enzyme inhibitors and an increased risk of lung cancer.

Cannabis oil

Cannabinoids have limited impact on MS symptomsSubscription

Following a systematic review and meta-analysis researchers have concluded that cannabinoids have limited therapeutic effect on symptoms of multiple sclerosis

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Raised urate levels more strongly linked to genetics than diet, study findsSubscription

Diet contributes much less towards the development of high serum urate levels than genetic factors, study results reported in The BMJ suggest.

Man doing spirometry test for COPD

Triple therapy cuts exacerbations in COPD regardless of baseline reversibilitySubscription

Triple therapy reduces the number of moderate-to-severe exacerbations in people with chronic obstructive pulmonary disease, a study presented at the CHEST annual meeting has shown.

Obese people

Weight loss drug reduces risk of diabetes in overweight and obese peopleSubscription

Taking lorcaserin and making lifestyle changes can help prevent diabetes in people who are overweight or obese, study findings indicate.

Urine dipstick test

New antibiotic effective against multi-drug resistant Gram-negative UTISubscription

A new antibiotic designed to overcome multi-drug resistance is at least as effective as the current standard of care in complicated urinary tract infection, according to trial results published in The Lancet Infectious Diseases.

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